CSL shifts gene therapy focus, closes Pasadena site

19 November 2024

Australia’s CSL Limited (ASX: CSL) plans to shut down its Californian R&D facility focused on cell and gene therapies by January 2025, signaling a shift away from ex vivo lentiviral-based technology.

The Pasadena site, originally acquired in 2017 through CSL's purchase of Calimmune, has been instrumental in developing hematopoietic stem cell gene therapies.

Since the acquisition, the site has expanded to include advanced cell manufacturing capabilities and laboratory operations. Moving forward, CSL intends to centralize these functions at its Waltham, Massachusetts, facility, aligning with its investment in self-amplifying mRNA and lipid nanoparticle technologies.

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