Roche ready to go into Phase III with Alzheimer’s prospect

4 April 2025

Swiss pharma giant Roche’s (ROG: SIX) Genentech subsidiary has presented new data at the AD/PD 2025 International Conference on Alzheimer’s and Parkinson’s Diseases in Vienna, Austria.

The data included presentations from the ongoing trontinemab Phase Ib/IIa Brainshuttle AD study demonstrating dose-dependent rapid amyloid depletion from the brain, and the potential of the Elecsys pTau181 plasma test to rule out amyloid pathology.

Based on the totality of data now accumulated, Roche says that the company will begin a Phase III program for trontinemab later this year.

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