Research shows need for better mpox protection in HIV-positive patients

4 April 2025

A new report from GlobalData has raised concerns over the effectiveness of mpox vaccines for people living with HIV.

Findings from a recent study published in The Lancet Infectious Diseases show that a single dose of Jynneos (smallpox and mpox vaccine) offered only 35% protection against mpox infection in HIV-positive individuals, compared with 84% in HIV-negative participants.

The jab, developed by Danish company Bavarian Nordic (CPH: BAVA), was originally offered for smallpox and has since been approved for mpox.

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