To QALY or not to QALY—does ICER's methodology risk patient access?

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Love it or loathe it, the Institute for Clinical and Economic Review (ICER) is not about to go away.

Founded in 2006, this small non-profit research organization in Boston, Massachusetts, has quietly taken on a significant amount of sway in pricing negotiations in the enormous US market for prescription pharmaceuticals.

Claiming to be independent and non-partisan, it is financed by a mixture of charitable donations and industry sources. Funding from foundations, which makes up about 80% of the total, comes from the Laura and John Arnold Foundation, the Blue Shield of California Foundation and others.

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