KOLs' advice on early-stage trials of novel agents for glioblastoma
Limitation of the blood brain barrier and difficulty in designing reliable early-stage trials has always been the major barriers for developers in formulating novel agents for glioblastoma multiforme (GBM).
As a result, drug makers in the GBM space must bolster the screening procedure for early-stage trials in a more efficient way and demonstrate a clear benefit for patients to push their pipeline agents for the most lethal form of brain cancer through to the finish line, says data and analytics company GlobalData.
Despite the abundance of approvals and launches of novel therapies in the oncology space, no new drugs for GBM were launched since the approval in 2009 of now Roche (ROG: SIX) subsidiary Genentech’s Avastin (bevacizumab).
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