Novogen in-licenses glioblastoma drug candidate from Genentech

31 October 2016

Shares of Australian oncology-focused biotech Novogen (ASX: NRT) rose 11.1% to A$0.09 today, after the company revealed it has entered into a worldwide licensing agreement with Genentech, a subsidiary of Swiss pharma giant Roche (ROG: SIX), to develop and commercialize GDC-0084, a small molecule inhibitor of the phosphoinositide-3-kinase (PI3K) pathway.

The lead indication for GDC-0084 is glioblastoma multiforme (GBM), which is the most aggressive form of brain cancer, accounting for around 15% of primary brain tumours. Median overall survival is considered to be about 12-15 months from the time of diagnosis.

Will pay an initial $5 million to Genentech

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