UCB and Biogen’s dapirolizumab pegol paves new path for SLE treatment

13 November 2024

Belgian drugmaker UCB (Euronext: UCB) and US biotech Biogen’s (Nasdaq: BIIB) Phase III PHOENYCS GO trial results signal a pivotal development for systemic lupus erythematosus (SLE) treatment, as dapirolizumab pegol met its primary endpoint and demonstrated enhanced disease control and safety at Week 48.

With a novel CD40L-targeting mechanism and favorable efficacy outcomes, this therapy has the potential to challenge established SLE treatments and address unmet needs in an increasingly competitive therapeutic landscape, according to pharma analytics company GlobalData.

The findings of this trial, which constitute a significant milestone for the companies, which will debut as a late-breaking abstract at the upcoming American College of Rheumatology (ACR) 2024 congress, taking place on November 14-19, 2024.

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