The week in pharma: action, reaction and insight – week to February 11, 2022

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By Barbara Obstoj-Cardwell. Editor

Research news last week saw US cancer focussed firm Karyopharm Therapeutics release a bullish review of new Phase III data on its endometrial cancer candidate selinexor. Financial results were also in focus. Pfizer, the world’s largest prescription medicines maker last Tuesday reported record fourth quarter 2021 figures, boosted by its hugely successful covid vaccine Comirnaty but issued conservative longer-term guidance. UK-based AstraZeneca also announced financials which pleased markets but also raised some questions regarding its vaccine rollout. On the regulatory front, a US Food and Drug Administration advisory committee voted against approval of Eli Lilly and Innovent’s lung cancer candidate sintilimab, citing the grounds of a China-based clinical trial backing the application as not appropriate.

Karyopharm fishes for a win as its solid tumor bid flounders

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