Phase II data could support bid for selinexor approval in DLBCL

20 June 2019
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US drugmaker Karyopharm Therapeutics (Nasdaq: KPTI) has reported updated results from the Phase IIb SADAL study of selinexor at the International Conference on Malignant Lymphoma (ICML) in Switzerland.

The first-in-class, oral Selective Inhibitor of Nuclear Export (SINE) compound is being tested as a third-line option for certain people with relapsed or refractory diffuse large B-cell lymphoma (DLBCL).

The detailed results are in line with top-line data reported at the December 2018 American Society of Hematology (ASH) annual meeting.

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