Bulk of trial data validates anti-depressant use, says meta-analysis
A systematic review and network meta-analysis of 522 randomized controlled trials of 21 drugs used to treat major depressive disorder (MDD) in adults has been published in The Lancet, revealing that their use has brought benefits compared to placebo.
The results have been picked up by news sources internationally and appear to validate the use of these drugs in MDD rather than psychological or other interventions.
All 21 drugs were found to be better at reducing symptoms than placebo, ranging from being a third to more than twice as effective.
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