Lilly's Ebglyss demonstrated meaningful improvement in eczema

25 October 2024

New results show Eli Lilly (NYSE: LLY) Ebglyss (lebrikizumab-lbkz) improved skin (including hand and face) and itch among patients with moderate-to-severe atopic dermatitis (eczema) who were previously treated with Dupixent (dupilumab).

These results from the Phase IIb ADapt study are being presented at the Fall Clinical Dermatology (FCD) Conference from October 24-27 in Las Vegas, USA

Lilly explained that the cytokine interleukin (IL)-13 is key in atopic dermatitis, driving the type-2 inflammatory cycle in the skin, leading to skin barrier dysfunction, itch, skin thickening and infection. Lilly acquired rights to the drug in 2020, along with its $1.1 billion buy of Dermira, which in turn had licensed it from Roche (ROG: SIX).

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