Strategic overhaul at Acelyrin after late-stage success

14 August 2024

Acelyrin (Nasdaq: SLRN) has announced that its Phase III trial for izokibep in hidradenitis suppurativa (HS) met the primary endpoint, achieving a measure of efficacy at 12 weeks.

Despite this success, the company will shift its focus towards advancing lonigutamab for thyroid eye disease, a strategic move projected to extend its cash runway until mid-2027.

The company plans to complete its ongoing trials for izokibep but will not pursue further investment in the HS and psoriatic arthritis indications.

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