Positive late stage data for nipocalimab in myasthenia gravis

16 October 2024

Johnson & Johnson (NYSE: JNJ) has reported positive results from its Phase II/III Vibrance-MG trial, setting up potential competition in the treatment of generalized myasthenia gravis (gMG).

gMG is a lifelong autoimmune neuromuscular disorder characterized by muscle weakness that worsens with activity and improves with rest.

The American pharma major is testing the FcRn blocker nipocalimab, with results from the trial showing people aged 12 to 17 achieved sustained disease control when treated with nipocalimab plus standard of care.

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