Astellas partners with Sangamo on cutting-edge gene therapy

20 December 2024

Astellas Pharma (TYO: 4503) has struck a licensing agreement with Sangamo Therapeutics (Nasdaq: SGMO) to make use of its neurotropic adeno-associated virus capsid, STAC-BBB.

This innovative technology, designed to penetrate the blood-brain barrier, aims to enable the development of genomic medicines for neurological diseases.

Japan’s Astellas will gain worldwide rights to use STAC-BBB for one neurological target, with options to expand to four additional targets, paying $20 million right away and up to $1.3 billion in milestones. Sangamo will also receive tiered royalties on sales of any marketed products.

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