More fallout from epacadostat failure as Bristol-Myers drops IDO blocker

2 May 2018

New York’s Bristol-Myers Squibb (NYSE: BMY) is reportedly the latest drugmaker to step away from development of IDO blockers, a once promising field of immuno-oncology research that has hemorrhaged support since Incyte (Nasdaq: INCY) announced a bruising Phase III failure in this area last month.

The firm said it would curtail development activities related to BMS-986205, an IDO inhibitor acquired as part of its 2015 buyout of privately-held US biotech Flexus.

A spokesperson for Bristol-Myers told press the firm had “closed registrational studies of our IDO inhibitor, BMS-986205, in melanoma, SCCHN and NSCLC.”

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