USA-based biopharma company ImmunogenX says it has completed the acquisition of the non-cash assets of privately-held celiac disease (CD) specialist Alvine Pharmaceuticals.
This includes latiglutenase (formerly known as ALV003 and renamed IMGX-003), an orally administered mixture of two recombinant gluten-specific proteases that degrades gluten proteins into small physiologically irrelevant fragments. The technology is backed by over 50 issued or pending patents, has been extensively studied in Phase I and Phase II clinical trials, and is the only CD treatment that has demonstrated histologic success as well as symptomatic improvements in clinical trials.
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