iBio uses iBioLaunch technology to produce functional MAb copy of Synagis
US biotech firm iBio (NYSE AMEX: IBIO) says that its proprietary iBioLaunch technology for the production of biotherapeutic proteins and vaccine antigens in whole green plants has been used to produce a functional monoclonal antibody copy of palivizumab.
Palivizumab, the active ingredient AstraZeneca (LSE: AZN) subsidiary MedImmune’s Synagis, is a humanized monoclonal antibody that binds to respiratory syncytial virus (RSV) glycoprotein fusion protein (F), and inhibits viral entry into cells. Palivizumab is used to reduce RSV associated hospitalizations, but its high cost limits treatment to high-risk infants who receive monthly intramuscular injections throughout the RSV season. Worldwide annual sales of palivizumab, the patent on which does not expire until 2015, exceed $900 million a year, according to iBio.
Partnered with Fraunhofer USA Center
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