Lexicon pivots back to pipeline after FDA rejection

25 November 2024

Lexicon Pharmaceuticals (Nasdaq: LXRX) has announced a major strategic shift, prioritizing its late-stage pipeline following a rejection by the US Food and Drug Administration.

The agency has rebuffed a bid to market Zynquista (sotagliflozin) as an adjunct to insulin in adults with type 1 diabetes and chronic kidney disease.

The company said it would now eliminate its commercial field team and wind down promotional efforts for Zynquista and Inpefa (sotagliflozin), which was approved last year for heart failure.

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