Homology soars as it considers strategic options

31 July 2023
homology_medicines_large

Shares in US genetic medicines company Homology Medicines (Nasdaq: FIXX) leapt more than 35% to $1.34 last Friday, after it revealed it has completed a review of its business, and the board of directors has approved a plan to evaluate strategic alternatives to maximize shareholder value.

Earlier the same day,  Homology reported encouraging initial data from the first dose level in the Phase I, dose-escalation trial evaluating gene editing candidate HMI-103 in adults with classical phenylketonuria (PKU), which showed it was generally well-tolerated in all three participants and resulted in a meaningful reduction in plasma phenylalanine (Phe) in two participants as of the data cut-off date of July 26, 2023.

Despite these encouraging data, Homology said that, based on the current financing environment and the company’s anticipated clinical development timelines, it will not be further developing its programs and will be instituting a related reduction in force while it explores options for the company and its assets, including HMI-103. Homology has retained TD Cowen as its strategic financial advisor.

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK

Companies featured in this story

More ones to watch >


Today's issue

Company Spotlight





More Features in Biotechnology