Belgian biotech Galapagos (Euronext: GLPG) plans to divide into two distinct entities, separating its cell therapy operations from a new spin-off company.
The move, expected to complete by mid-2025, includes job cuts affecting 40% of its workforce and a closure of its French site. The firm will also abandon small-molecule drug development, including TYK2 inhibitor GLPG3667, for which a partner will be sought.
The company’s current cell therapy business will remain under the Galapagos banner, focusing on oncology treatments like the CAR-T candidate GLPG5101, which showed promising results in a Phase I/II trial for relapsed/refractory non-Hodgkin lymphoma.
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