Swiss pharma giant Novartis (NOVN: VX) recently announced new anticipated long-term positive data for its one-time infusion gene therapy, Zolgensma (onasemnogene abeparvovec-xioi), which is set to help the drug generate global sales of $2.5 billion by 2025 and lead the spinal muscular atrophy (SMA) market, says data and analytics company GlobalData.
The data showed significant therapeutic benefit in patients with SMA over a range of extended studies, covering patients treated pre-symptomatically, and sustained durability in patients up to five years post-dosing. Interim results were also reported of an intrathecal formulation testing in older patients with SMA type 2 aged two to five.
Sarah Elsayed, pharma analyst at GlobalData, commented: “The robust overall trial results are expected to spur the drug's sales, expand its future patient pool and further dispel controversies raised over the drug’s credibility after its pre-clinical data manipulation incident and $2.1 million price tag.’’
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze