Disappointment for ArQule and Daiichi Sankyo in Phase III study

17 February 2017
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American biotech firm ArQule (Nasdaq: ARQL) and Japanese pharma major Daiichi Sankyo (TYO: 4568) today announced that their Phase III study into experimental anti-cancer agent tivantinib did not meet the primary endpoint of improving overall survival.

The study analyzed a total of 340 patients with hepatocellular carcinoma (HCC), the most prevalent form of liver cancer. Full results from the trial will be presented at an upcoming scientific forum, the companies said.

“HCC is a disease with high unmet need, especially in the second-line setting, so these results are disappointing for the patients as well as the investigators and the companies,” said Paolo Pucci, chief executive of ArQule.

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