US pharma major Bristol Myers Squibb (NYSE: BMY) has revealed details results of the Phase III CheckMat -816 trial in patients with resectable non-small cell lung cancer (NSCLC).
This data showed that neoadjuvant treatment with three cycles of Opdivo (nivolumab) in combination with chemotherapy, significantly improved event-free survival (EFS), a primary endpoint, compared to chemotherapy alone.
"These findings, combined with the improved survival outcomes, have the potential to completely change the way surgeons and oncologists collaborate in treating patients with resectable NSCLC"With a minimum follow-up of 21 months, Opdivo with chemotherapy reduced the risk of disease recurrence, progression or death by 37% across randomized patients when administered before surgery. In patients receiving the combination, median EFS was 31.6 months, compared to 20.8 months for patients treated with chemotherapy alone.
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