US oncology immunotherapy specialist Advaxis (Nasdaq: ADXS) has granted Sellas Life Sciences Group a license to develop a novel cancer immunotherapy agent using Advaxis’ proprietary Lm-based antigen delivery technology with the Swiss/Greek pharmaceutical and clinical research company’s patented WT1 targeted heteroclitic peptide antigen mixture (galinpepimut-S).
The news pushed Advaxis’ shares 10.16% higher to $9.32 by mid-morning today.
Advaxis’ proprietary technology generates innate immune stimulation, alongside potent and sustained T-cell responses. When combined with Sellas’ WT1 antigens, this has the potential to precisely direct an immune response, yielding improved clinical activity against many cancer types that express WT1. Sellas’ future clinical studies will investigate this capability in the presence of measurable residual or recurrent disease.
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