Hengrui deal expands Merck’s cardio-metabolic pipeline

25 March 2025

US pharma giant Merck & Co (NYSE: MRK) and China’s Jiangsu Hengrui Pharmaceuticals (SHA: 600276) have entered into an exclusive license agreement for HRS-5346.

Hengrui’s investigational oral small molecule lipoprotein(a), or Lp(a), is inhibitor currently being evaluated in a Phase II trial in China.

Under the agreement, Hengrui has granted Merck exclusive rights to develop, manufacture and commercialize HRS-5346 worldwide, excluding in the greater China region.

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