Verrica Pharma announces positive preliminary top-line results for VP-315

14 August 2024

Shares of American dermatology company Verrica Pharmaceuticals (Nasdaq: VRCA) had a roller-coaster start to the day after announcing what it called positive trial results, leaping 23% pre-market but plunging 27.8% to $3.80 by late morning trading when it also announced financials.

Verrica released preliminary positive results from Part 2 of its Phase II clinical trial studying VP-315, a potential first-in-class oncolytic peptide, for the treatment of basal cell carcinoma (BCC), licensed from Norwegian firm Lytix Biopharma.

The study investigated drug candidate in BCC patients and shows impressively an: 86% overall reduction of tumor size; 51% complete clearance rate of basal cell carcinomas (total removal); and 1% average reduction in tumor size of patients with residual carcinomas

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