Strong data on Phytopharm's Cogane in ALS

17 January 2012

UK drug developer Phytopharm (LSE: PYM) yesterday announced preliminary data indicating that Cogane (PYM 50028) has demonstrated efficacy in a genetic preclinical model of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, the most common form of motor neurone disease.

The study was performed in a model that has a mutation in the SOD1 gene (SOD1G93A); mutation of the SOD1 gene is a known cause of ALS in humans. In this study Cogane was administered orally for 50 days, commencing after ALS type symptoms were manifest. This is therefore considered to be a model of severe, late-stage ALS.

Main findings:

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