Sanofi and Regeneron report positive Phase III results with sarilumab in RA

22 November 2013

French drug major Sanofi (Euronext: SAN) and US partner Regeneron Pharmaceuticals (Nasdaq: REGN) have reported positive results from a Phase III trial of sarilumab in rheumatoid arthritis (RA).

The SARIL-RA-MOBILITY trial in adult patients with active rheumatoid arthritis who were inadequate responders to methotrexate (MTX) therapy, showed that sarilumab, the first fully-human anti-IL-6R monoclonal antibody, treatment in combination with MTX improved disease signs and symptoms as well as physical function, and inhibited progression of joint damage.

Neil Graham, Regeneron’s vice president, Immunology and Inflammation, said: “IL-6 blockade is emerging as an important therapeutic approach for rheumatoid arthritis. We are encouraged with these Phase III results, which demonstrated efficacy at both doses of sarilumab, each administered every other week.”

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK

Companies featured in this story

More ones to watch >


Today's issue

Company Spotlight





More Features in Pharmaceutical