Spanish drugmaker PharmaMar (MC: PHM) has entered a licensing agreement with Eczacıbaşı Group to commercialize the marine-derived anticancer drug Aplidin (plitidepsin) in Turkey.
Under the terms of the accord, PharmaMar will receive an undisclosed upfront payment as well as development milestones related to the health approval procedure of Aplidin in this country. PharmaMar will retain exclusive production rights and will supply the finished product to Eczacıbaşı for commercial use.
Aplidin is PharmaMar´s second most advanced anticancer drug currently under development for the treatment of multiple myeloma and angioimmunoblastic T-cell lymphoma. The company announced in March 2016 that plitidepsin has shown positive results in a pivotal Phase III clinical trial (ADMYRE) for multiple myeloma and in September 2016, PharmaMar presented to the European Medicines Agency the submission of the Marketing Authorization Application for this drug in combination with dexamethasone for the treatment of relapsed/refractory multiple myeloma (MM).
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