Pfizer's oral Xeljanz meets endpoints in Phase III ulcerative colitis trials
US pharma giant Pfizer (NYSE: PFE) on Friday released positive clinical trial results for its rheumatoid arthritis drug Xeljanz (tofacitinib) in the treatment of ulcerative colitis, which could result in an expanded indication for the already marketed drug.
The ulcerative colitis market is expect to grow to a value of $4.2 billion in the top seven markets (USA, France Germany, Italy, Spain, the UK and Japan), accorded to research from Decision Resources. For full-year 2015, Xeljanz generated sales of $523 million. The firm’s shares edged up 1.03% to $29.54 by closed of trading.
Results from OCTAVE Induction 1 and OCTAVE Induction 2, evaluating the efficacy and safety of oral tofacitinib 10mg twice daily (BID) in inducing remission in adult patients with moderately to severely active ulcerative colitis (UC) were presented the 11th Congress of European Crohn's and Colitis Organization (ECCO).
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