US drug major Eli Lilly (NYSE: LLY) said combination late stage trials for its Trulicity (dulaglutide), to treat type 2 diabetes, has demonstrated it to be significantly effective versus treatment with sulfonylurea alone.
Kathleen Dungan, endocrinologist, associate professor, The Ohio State University Wexner Medical Center, and lead study author, said: "For patients who cannot tolerate or have contraindications to metformin, a sulfonylurea is often prescribed as first-line therapy for type 2 diabetes. This study affirms that Trulicity is efficacious and well-tolerated as an add-on to sulfonylurea therapy, which can help prescribers make treatment decisions for their individual patients."
The most commonly reported adverse events were gastrointestinal-related and consistent with prior Trulicity studies, including nausea (10.5%) and diarrhoea (8.4%). There were no cases of pancreatitis or pancreatic cancer in either treatment group.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze