Negative NICE view on Venclyxto

26 October 2018
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There was disappointing news today for US biopharma company AbbVie (NYSE: ABBV), when the UK cost-effectiveness body said it does not recommend its leukemia drug for National Health Service use, and sending its share price down 1.96% to $80.13 by late morning.

Draft guidance issued today by the National Institute for Health and Care Excellence (NICE) does not recommending Venclyxto (venetoclax) plus rituximab for the treatment of relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) in adults.

Venclyxto, which costs £4,789 ($6,183) for 28 days’ supply at full price, did not qualify for extra leniency from the NICE where a medicine extends the life expectancy in patients with a few months left to live. Despite a commercially confidential discount, the NICE said the drug was not cost effective, although the manufacturer has until mid-November to submit further evidence.

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