Importance of continued Brilinta treatment beyond one year of a heart attack
A sub-analysis of the PEGASUS-TIMI 54 study, assessing the effect of Brilinta (ticagrelor) in reducing atherothrombotic events in post-heart attack patients, based on the time from withdrawal of their previous P2Y12 inhibitor antiplatelet therapy, has been released by Anglo-Swedish pharma major AstraZeneca (LSE: AZN).
Current European guidelines recommend that dual antiplatelet therapy is stopped 12 months after a heart attack. The PEGASUS-TIMI 54 study enrolled patients who had suffered a heart attack one to three years previously.
The data, presented during a Clinical Trial Update hotline session at European Society of Cardiology (ESC) Congress 2015, demonstrated that withdrawal from P2Y12 inhibitor antiplatelet therapy is associated with heightened risk of ischemic events, including cardiovascular death, myocardial infarction or stroke.
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