Erasca signs collaboration with Novartis

15 February 2024
erasca_big

San Diego, USA-based precision oncology company Erasca (Nasdaq: ERAS) announced two clinical trial collaboration and supply agreements (CTCSAs) with Swiss pharma giant Novartis (NOVN: VX) for the MEK inhibitor Mekinist (trametinib), with the news edging Erasca’s shares up 3.6% to $1.73 by close of trading on Wednesday.

Erasca noted that the accord will support the clinical development of the pan-RAF inhibitor naporafenib in combination with trametinib for the treatment of patients with RAS Q61X solid tumors in the Phase Ib SEACRAFT-1 trial and in patients with previously treated NRAS-mutant (NRASm) unresectable or metastatic melanoma in the randomized, pivotal Phase III SEACRAFT-2 trial.

Erasca is sponsoring the trials, and Novartis is supplying its already marketed cancer drug trametinib at no cost. No financial terms of the collaboration have been disclosed.

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK

Companies featured in this story

More ones to watch >


Today's issue

Company Spotlight





More Features in Pharmaceutical