Anavex confirms positive preclinical data for lead candidate ANAVEX 2-73 in epilepsy

10 February 2015

Neurological biopharma company Anavex Life Sciences has confirmed positive preclinical data for lead candidate ANAVEX 2-73 in epilepsy.

This also validates the compound as a prospective platform drug for other neurodegenerative diseases aside from Alzheimer’s. The data shows significant improvement in reducing seizures relative to three generations of epilepsy drugs on the market. The drug has completed a Phase I human clinical trial, and is currently in Phase IIa for Alzheimer’s disease.

Alone, ANAVEX 2-73 showed significant anticonvulsive dose-dependent action by providing almost complete protection from tonic seizures, and in maximum electroshock-induced convulsions it was observed that 30mg/kg ANAVEX 2-73 was able to provide 90% protection.

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