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Galecto

A clinical-stage company incorporated in the U.S. that is developing small molecule-based inhibitors of galectin-3 and LOXL2.

As of August 2023, Galecto has multiple ongoing Phase II clinical programs in fibrosis and cancer, including an orally active LOXL2 inhibitor (GB2064) in a Phase IIa trial for the treatment of myelofibrosis; an orally active galectin-3 inhibitor (GB1211) in a recently completed Phase Ib/IIa trial in liver cirrhosis; and an orally active galectin-3 inhibitor (GB1211) in combination with atezolizumab (Tecentriq) in a separate Phase IIa trial for the treatment of NSCLC.

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