Pharmaceutical Despite previous rejections of its advances, Japanese drug major Astellas Pharma this morning said it plans to acquire USA-based OSI Pharmaceuticals for $52.00 per share in cash, or an aggregate of some $3.5 billion on a fully diluted basis, representing a significant premium of over 40% on the closing price of OSI's common stock of $37.02 per share on February 26, 2010, a 53% premium to its three-month average of $34.01 per share, and a 31% premium to its 52-week high of $39.66 per share. Astellas' hostile tender offer to shareholders, which is not subject to any financing conditions, will commence tomorrow, the firm stated. 1 March 2010