First-in-class treatment approved by NICE for allergic rhinitis

30 January 2025

UK health technology assessor the National Institute for Health and Care Excellence (NICE) has recommended Acarizax (12 SQ-HDM SLIT, also known as ‘sublingual immunotherapy’) for the treatment of moderate to severe house dust mite allergic rhinitis disease in people 12 to 65 years that is persistent despite symptom-relieving medicine.

Developed by Danish allergy specialist ALK-Abello (OMX: ALK), whose shares edged up 2.6% to 155.70 kroner in early trading, 12 SQ-HDM SLIT is the first treatment of its kind to be approved by NICE. This decision paves the way for patient access to this therapy through the National Health Service (NHS), the company noted.

Allergic rhinitis disease is a prevalent condition in the UK, affecting about 26% of adults. Among these, house dust mite is the most common airborne allergy, affecting around half of those living with allergic rhinitis disease – upwards of 5 million people in the UK. Despite a range of symptomatic treatment options, approximately one million people still live with debilitating and uncontrolled symptoms.

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