ESMO 2024: Novartis’ Kisqali shows deepening benefit beyond three-year treatment period
Swiss pharma giant has shared a well-timed updated analysis from the pivotal Phase III NATALEE trial at the European Society for Medical Oncology (ESMO) Congress 2024.
The update shows that investigational Kisqali (ribociclib) alongside endocrine therapy (ET) shows a deepening benefit beyond the three-year treatment period, reducing the risk of recurrence by 28.5%, compared to ET alone, in patients with stage II and III hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) early breast cancer.
This invasive disease-free survival benefit was also consistent across all pre-specified patient subgroups, including those with node-negative disease.
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