The week in pharma: action, reaction and insight - week to October 29, 2021

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By Barbara Obstoj-Cardwell

Apart from financial results, clinical trial results were much in evidence among the news last week. Novartis’ already-marketed canakinumab missed Phase III clinical goals in lung cancer for a second time. Sanofi and Regeneron released new data on their Dupixent in the treatment of eosinophilic esophagitis along with plans for regulatory filings. Also, there was disappointment in the Alzheimer’s space, when US biotech Cortexyme last Tuesday reported missed endpoints in a Phase II/III of its candidate atuzaginstat. Meantime, the announcement that Alnylam’s long-time chief executive John Maragonore was leaving after 19 years came as a big surprise.

Novartis won’t can canakinumab

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