Tagrisso tops triple-dose of AstraZeneca ASCO data

3 June 2024

Positive results have been presented from the LAURA Phase III trial on AstraZeneca’s (LSE: AZN) Tagrisso (osimertinib) at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting.

The EGFR inhibitor showed a statistically-significant and highly clinically-meaningful improvement in progression-free survival (PFS) for patients with unresectable, Stage III epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC) whose tumours have exon 19 deletions or exon 21 (L858R) mutations, after chemoradiotherapy (CRT) compared to placebo after CRT.

Results showed Tagrisso reduced the risk of disease progression or death by 84% compared to placebo. Median PFS was 39.1 months in patients treated with Tagrisso versus 5.6 months for placebo.

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