News that Eisai (TYO: 4523) and Biogen’s (Nasdaq: BIIB) anti-amyloid beta (Aβ) monoclonal antibody (MAb) lecanemab was effective in reducing cognitive clinical decline among patients with early Alzheimer’s disease (AD) in the Phase III Clarity AD trial (NCT03887455), resulted in a positive market reaction.
Biogen jumped by as much as 44% and Eisai climbed 17%.
The prospects for lecanemab were further endorsed by a report from analytics firm GlobalData, whose senior neurology analyst Pippa Salter noted that, after multiple failures, and the controversial approval and messy launch of Biogen’s anti-Aβ MAb Aduhelm (aducanumab), lecanemab has finally demonstrated in a large-scale pivotal trial that targeting Aβ can be a successful way to treat AD.
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