Shire in strategic collaboration with ArmaGen for Hunter syndrome

23 July 2014

Ireland-headquartered drugmaker Shire (LSE: SHP) has entered into an agreement with US privately held biotech company ArmaGen for the worldwide licensing and collaboration of AGT-182, an investigational enzyme replacement therapy. This would potentially be used to treat the central nervous system and somatic manifestations in patients with Hunter syndrome (MPS II).

Shire will obtain worldwide commercialization rights for AGT-182 in exchange for payments of approximately $225 million to ArmaGen, including an initial upfront of $15 million in cash and equity, an additional equity investment, research and development funding, development milestones and sales milestones, in addition to royalties.

Shire responsible for further development

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