Positive results for AstraZeneca's brodalumab to treat psoriasis

1 October 2015

Late stage trials for by Anglo-Swedish drug major AstraZeneca’s (LSE: AZN) brodalumab, to treat moderate to severe psoriasis, have shown positive results, according to a report published by the New England Journal of Medicine (NEJM).

Brodalumab is the only investigational treatment in development that binds to the interleukin-17 (IL-17) receptor and inhibits inflammatory signalling by blocking the binding of several IL-17 cytokines (A, F, A/F and C) to the receptor.

Bing Yao, senior vice president, R&D at MedImmune, AstraZeneca’s global biologics research arm, said: “Publication of these data in NEJM underscores the importance of brodalumab as a potential new treatment for people with psoriasis, a serious, chronic disease that can have an overwhelming, negative impact on patients’ lives. We look forward to progressing this novel molecule to regulatory submissions in the near future.”

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