Actelion, one of the Janssen companies of Johnson & Johnson (NYSE: JNJ), presented new data on its pulmonary drug yesterday at the American Thoracic Society (ATS) conference 2019.
A new post-hoc analysis from the GRIPHON study shows that adding Uptravi (selexipag) versus placebo improved long-term clinical outcomes regardless of time of treatment initiation, and demonstrated an even more pronounced treatment effect when initiated early. The GRIPHON study is the largest randomized, controlled, outcome trial ever conducted in patients with pulmonary arterial hypertension (PAH).
“This new analysis reinforces the overall efficacy data for selexipag and provides compelling evidence of the benefits of initiating selexipag early,” said Prof Sean Gaine, Consultant Respiratory Physician and Director of National Pulmonary Hypertension Unit, Mater Misericordiae University Hospital, Dublin, Ireland. “These data add to the growing evidence supporting early intensification of treatment, which is important when you consider that around a third of PAH patients currently die within five years of diagnosis. Early recognition and prompt treatment of the disease are key to achieving sustained long-term benefits,” he added.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze