Maze Therapeutics finds new partner for Pompe disease candidate

11 May 2024
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Privately-held Californian company Maze Therapeutics has found a new partner for its investigational Pompe disease candidate in the form of Japan’s Shionogi (TYO: 4507).

The companies have completed an exclusive worldwide license agreement for the rights to MZE001, an investigational oral glycogen synthase 1 (GYS1) inhibitor that aims to address Pompe disease by limiting disease-causing glycogen build-up.

The new partnership comes after a setback last December, when the US Federal Trade Commission (FTC) filed a complaint seeking to block Sanofi’s (Euronext: SAN) exclusive worldwide license agreement for Maze’s on GYS1 program, including MZE001, which led to the French drug major pulling out of the deal.

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