Sanofi (Euronext: SAN) has presented detailed results from the Phase III VOYAGE trial, showing that Dupixent (dupilumab) significantly reduced severe asthma attacks, and within two weeks rapidly improved lung function in children aged 6 to 11 years.
Dupixent is a fully human monoclonal antibody that inhibits the signaling of the interleukin-4 (IL-4) and interleukin-13 (IL-13) pathways.
The trial has been testing the impact of the therapy in children with uncontrolled moderate-to-severe asthma, with evidence of type 2 inflammation.
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