Chi-Med's ASCO data thrusts fruquintinib forward
Hutchison China MediTech (Nasdaq: HCM) has announced results from its pivotal Phase III trial of fruquintinib, its novel vascular endothelial growth factor receptor (VEGFR) kinase inhibitor in an oral presentation at ASCO 2017.
Results showed that FRESCO, a randomized, double-blind, placebo-controlled, multi-centered Phase III trial assessing fruquintinib in patients with locally-advanced or metastatic colorectal cancer in China, met all primary and secondary endpoints including significant improvements in overall and progression-free survival with a manageable safety profile and lower off-target toxicities compared to other targeted therapies.
"Particularly encouraging was that fruquintinib showed relatively low frequency and less severe liver function abnormalities compared with other targeted therapies used in this disease setting"
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