Cellics to get up to $15 million to develop a nanosponge treatment for sepsis
Antibiotics accelerator CARB-X is awarding up to $3.9 million to privately-held Cellics Therapeutics to develop a new treatment for sepsis caused by drug-resistant Gram-positive and Gram-negative bacteria.
The Californian company will be eligible for an additional $11.05 million for a total up to $15 million in non-dilutive funding from the non-profit agency, if project milestones are met, subject to available funds.
Cellics’ innovative nanosponge project uses the natural receptors on human macrophage membranes – a type of white blood cell in the immune system – to soak up and neutralize bacterial toxins and inflammatory cytokines that can cause sepsis. The project, CTI-111, is designed as an adjunct in combination with antibiotics and other medicines.
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