Abbvie and FutureGen team up on IBD drug

13 June 2024

US drugmaker AbbVie (NYSE: ABBV) and China’s FutureGen Biopharmaceutical have announced a license agreement to develop FG-M701, a next generation TL1A antibody for the treatment of inflammatory bowel disease (IBD), currently in pre-clinical development.

FG-M701 is a fully human monoclonal antibody targeting TL1A, a clinically validated target in IBD. It is uniquely engineered with potential best-in-class functional characteristics compared to first-generation TL1A antibodies, with the goal to drive greater efficacy and less frequent dosing as a therapy for IBD.

Jonathon Sedgwick, senior vice president and global head of discovery research, AbbVie, said: “The prevalence of IBD continues to increase, and many people living with ulcerative colitis and Crohn's disease do not respond to current therapies.

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